From the NASA website:
"NASA Commander Mark Kelly Appears at U2360° in Seattle
U2 delivered a surprise to the crowds at Quest Field, Seattle last night with a video message from Commander Mark E. Kelly. Bono dedicated 'Beautiful Day' to Gabby Giffords, before asking, “Imagine a man looking down on us from 200 miles up. Looking down at our beautiful crowded planet… What would he say to us…? What is on your mind Commander Kelly?”
Commander Kelly, on a 16-day mission with the Endeavour crew, recorded the message aboard the International Space Station, 'Hello Seattle… from the International Space Station.' Before finishing on a line from David Bowie's 'Space Oddity' : 'I’m looking forward to coming home. Tell my wife I love her very much… she knows.'"